Key result
Type D personality predicted the development of the first peritonitis in continuous ambulatory peritoneal dialysis patients (HR 1.67; 95% CI 1.07-2.59; p = 0.022).
Why the study?
The study was conducted to investigate the association among Type D personality, medication adherence, and peritonitis in continuous ambulatory peritoneal dialysis patients.
Does Type D personality reduce medication adherence and increase peritonitis risk in continuous ambulatory peritoneal dialysis patients?
Cohort (n=385)
Does Type D personality reduce medication adherence and increase peritonitis risk in continuous ambulatory peritoneal dialysis patients?
Hazard Ratio: 1.67 (95% CI 1.07–2.59)
p-value: p=0.022
Type D personality is significantly associated with poorer medication adherence and a higher risk of developing peritonitis in CAPD patients.
May flag Type D CAPD patients for adherence support; leaves open whether screening reduces peritonitis.
The present study attempted to investigate the association among Type D, medication adherence and peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients. Type D personality was assessed by the Chinese 14-item Type D Personality Scale (DS14) in CAPD patients. Patients’ medication adherence was assessed by the Medication Adherence Report Scale, retrospectively. Of the 385 CAPD patients who were investigated, 137 (35.6%) patients had a Type D personality. The medication adherence was significantly poorer in the Type Ds compared with that of the non-Type Ds (21.5 ± 2.8 vs. 22.5 ± 2.5 score, p = 0.002). Using multiple linear regression analysis, we found that Type D personality was independently associated with medication adherence (β = 0.56, p < 0.05). Furthermore, the overall peritonitis-free survival rate of non-Type Ds was significantly higher than that of Type Ds (X2 = 4.41, p = 0.025). Using Cox regression, Type D personality (HR 1.67; 95% confidence interval [CI] 1.07–2.59; p = 0.022) and adherence to bag exchange procedure (HR 1.54; 95% CI 1.11–2.14; p = 0.009) predicted the development of the first peritonitis, even after adjustment for confounders. The current study is the first to identify a strong association among Type D, medication adherence and peritonitis in CAPD patients.
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Li et al. (2019) conducted a cohort in continuous ambulatory peritoneal dialysis (CAPD) (n=385). Type D personality vs. non-Type D personality was evaluated on development of the first peritonitis (HR 1.67, 95% CI 1.07-2.59, p=0.022). Type D personality predicted the development of the first peritonitis in continuous ambulatory peritoneal dialysis patients (HR 1.67; 95% CI 1.07-2.59; p = 0.022).
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