Methoxylation of the 5‐position of indoles and indolines was investigated. Treatment of 5‐bromo‐iodoles and indolines with cuprous iodide and sodium methoxide in methanol/dimethylformamide afforded the corresponding methoxy compounds. This methoxylation reaction was applied to the new synthesis of serotonin.
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SAITO et al. (1979) studied this question.
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