An insertion/deletion in the porcine FGFR2 gene

The 7000-rad INRA-University of Minnesota porcine Radiation Hybrid panel was used to localize the FGFR2 gene on Sus scrofa chromosome 14 (SSC14). An insertion/deletion mutation of approximately 240 bp was detected in the porcine FGFR2 gene. This mutation consists of a repeat motif of 48 bp. In a short and long variant of this polymorphism, the motif was repeated either six or 11 times. The mutation was shown to follow a Mendelian mode of inheritance in 10 families including 48 pigs of Large White x Duroc origin.