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Three species of lichens belonging to Umbilicaria, i.e., U. angulata, U. caroliniana, and U. polyphylla, have been examined for their water-soluble polysaccharide consitituents by chemical and physico-chemical methods. The results showed that they contained a partially O-acetylated pustulan as a sole water-soluble polysaccharide. All the polysaccharide specimens obtained here showed a remarkable antitumour effect against the implanted Sarcoma-180 in mice.
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Nishikawa et al. (1970) studied this question.
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