What does this research mean for the field?

Preoperative self-reported anxiety or depression does not limit postoperative improvement in patient-reported outcomes at 12 months after total ankle arthroplasty, and these psychological symptoms resolve in the majority of patients post-surgery. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To investigate whether patients reporting anxiety or depression prior to total ankle arthroplasty experience inferior patient-reported outcomes 1 year after surgery.

September 7, 2026Foot & Ankle InternationalOpen Access

Preoperative Anxiety and/or Depression as a Predictor of Patient‑Reported Outcomes After Total Ankle Arthroplasty

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Authors

MSMads Sundet MEMarianne Lund Eriksen ISInger Storrønning

Discussion

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Overview

Retrospective cohort study finds equivalent functional improvement after total ankle arthroplasty regardless of baseline anxiety or depression, suggesting distress should not preclude surgery.

Key Points

To investigate whether patients reporting anxiety or depression prior to total ankle arthroplasty experience inferior patient-reported outcomes 1 year after surgery.
Retrospective cohort study of prospectively collected registry data from a single centre analyzing 300 patients undergoing total ankle arthroplasty.
Preoperative anxiety/depression was identified using the EQ-5D-3L item 5, and the primary outcome was the 12-month Manchester-Oxford Foot and Ankle Questionnaire (MOxFQ) score.
Multivariable linear regression with multiple imputation evaluated the association between baseline psychological distress and 12-month MOxFQ, adjusting for baseline MOxFQ, age, sex, and diagnosis.
Patients with baseline anxiety/depression (30%, n=90) had worse absolute 12-month MOxFQ scores (mean 30.2 vs 20.1; P < .001), but their functional improvement from baseline did not differ significantly from unaffected peers (ΔMOxFQ 41.3 vs 43.9; P = .40).
After adjusting for baseline characteristics and symptom severity, preoperative anxiety/depression was not independently associated with 12-month MOxFQ scores (β = 4.3; 95% CI −0.9 to 9.5).
Approximately two-thirds of patients reporting baseline anxiety or depression no longer reported these symptoms at 12 months post-surgery.

Cite This Study

Sundet et al. (2026) studied this question.

synapsesocial.com/papers/6a9e85a2c3034f961570dd35 https://doi.org/10.1177/10711007261473923

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September 7, 2026Foot & Ankle InternationalOpen Access

Preoperative Anxiety and/or Depression as a Predictor of Patient‑Reported Outcomes After Total Ankle Arthroplasty

View Full Paper

Ask AI

Bookmark

Authors

MSMads Sundet MEMarianne Lund Eriksen ISInger Storrønning

Discussion

Member takes

Overview

Retrospective cohort study finds equivalent functional improvement after total ankle arthroplasty regardless of baseline anxiety or depression, suggesting distress should not preclude surgery.

Key Points

To investigate whether patients reporting anxiety or depression prior to total ankle arthroplasty experience inferior patient-reported outcomes 1 year after surgery.
Retrospective cohort study of prospectively collected registry data from a single centre analyzing 300 patients undergoing total ankle arthroplasty.
Preoperative anxiety/depression was identified using the EQ-5D-3L item 5, and the primary outcome was the 12-month Manchester-Oxford Foot and Ankle Questionnaire (MOxFQ) score.
Multivariable linear regression with multiple imputation evaluated the association between baseline psychological distress and 12-month MOxFQ, adjusting for baseline MOxFQ, age, sex, and diagnosis.
Patients with baseline anxiety/depression (30%, n=90) had worse absolute 12-month MOxFQ scores (mean 30.2 vs 20.1; P < .001), but their functional improvement from baseline did not differ significantly from unaffected peers (ΔMOxFQ 41.3 vs 43.9; P = .40).
After adjusting for baseline characteristics and symptom severity, preoperative anxiety/depression was not independently associated with 12-month MOxFQ scores (β = 4.3; 95% CI −0.9 to 9.5).
Approximately two-thirds of patients reporting baseline anxiety or depression no longer reported these symptoms at 12 months post-surgery.

Cite This Study

Sundet et al. (2026) studied this question.

synapsesocial.com/papers/6a9e85a2c3034f961570dd35 https://doi.org/10.1177/10711007261473923

View Full Paper

Ask AI

Bookmark