Background: Subretinal injection of perfluorocarbon liquids (PFCL) can occur during vitreoretinal surgery. The long‐term effects of this complication are not well established. Methods: A case report is presented of a patient with retained subretinal perfluorodecalin following retinal detachment repair for a giant retinal tear. Results: In the early postoperative period, the macular retinal pigment epithelium (RPE) became opalescent in appearance and by 2 months postoperatively the patient developed macular RPE atrophy with resulting poor central vision. Conclusions: Toxicity of subretinal perfluorodecalin causing RPE atrophy is proposed. We recommend all traces of PFCL should be removed if possible.
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Lee et al. (1998) studied this question.
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