Pulmonary Hemorrhage in a Patient with Fibrillary Glomerulonephritis

FIBRILLARY glomerulonephritis is an unusual kidney disease characterized by infiltration of the mesangium and glomerular basement membrane by fibrillary deposits that are negative on Congo-red staining but are reactive for polyclonal immunoglobulins.1 2 3 4 5 The disorder is thought to be mediated by the local production or deposition of abnormal paraproteins.6 , 7 In the approximately 50 cases of this disorder that have been reported previously, there have been no instances of pulmonary or other extrarenal manifestations. We describe a patient with fibrillary glomerulonephritis who died of pulmonary hemorrhage and fibrosis. The finding of fibrillary deposits in the interstitium of the lung in this patient . . .