Epidemiologic studies on uterine cancer at Cancer Institute Hospital, Tokyo, Japan

Five hundred and seventy-two patients with uterine carcinoma, treated at the Department of Gynecology, Cancer Institute Hospital, Tokyo, were interviewed, and 200 healthy women were also interviewed as controls. The results are as follows: 1. the age at first intercourse is lower in the carcinoma group; 2. the carcinoma group showed increasing parity; 3. all the unmarried patients in the cervical carcinoma group have had sexual intercourse; 4. patients having had syphilis were more numerous in the uterine carcinoma group, and the Wasser-mann-positive patients were also significantly higher in this group; 5. the proportion of patients whose husbands had phimosis was higher in the cervical carcinoma group, and 6. the proportion of patients with uterine carcinoma who had mothers with uterine carcinoma was higher than the control group. It is concluded that uterine carcinoma has some genetic background and that early age at first intercourse and other cervical tissue contaminant factors are important.