TREATMENT OF INFLUENZAL MENINGITIS BRmsH intracisternal as well as intraventricular penicillin. Case 4 had 40,000 units of penicillin intrathecally for eight days and intramuscular penicillin, 320,000 units daily, for 17 days. After an immediate good response there was a recurrence of meningitis at the end of the third week, and this was controlled completely by much larger dosage. Cases 6, 7, 8, and 9 were given 40,000 units intrathecally daily and 960,000 units intramuscularly in three-hourly doses. In no case was there any evidence of meningeal reinfection after the illness was once under control, and in no case was intracisternal or intraventricular therapy required. In one case a severe convulsion occurred after the fifth intrathecal injection, but with no ultimate ill effect.
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F. H. M. Dummer (1949) studied this question.