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A new locus for autosomal recessive complicated hereditary spastic paraplegia (SPG26) maps to chromosome 12p11.1-12q14N This defined a single region of homozygosity co- segregating with the disease spanning 22.8 cM of chromosome 12p11.1-12q14,flanked by markers D12S59 and D12S1676 (multipoint LOD score = 5.1).N This HSP neuropathy represents a novel genetic entity designated SPG26.
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Philip A. Wilkinson (2005) studied this question.
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