A short synthesis of the 1,2,4-triazolo[1,5-a]pyrimidine antibiotic essramycin is described involving condensation of aminoguanidine with ethyl benzoylacetate to give an amino-1,2,4-triazole, followed by condensation with ethyl acetoacetate to form the pyrimidone ring.
No takes yet. Share an insight, caveat, or question.
Battaglia et al. (2010) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: