Key result
A 27-year-old male with end-stage renal disease developed chronic constrictive pericarditis and expired despite partial and total pericardiectomy, highlighting a rare clinical association.
Case Report (n=1)
End-stage renal disease is a rare but potential cause of chronic constrictive pericarditis, which can have a fatal course despite surgical intervention.
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ESRD may rarely cause fatal constrictive pericarditis despite pericardiectomy; leaves open whether screening alters outcomes in dialysis patients.
Pericardial involvement in end-stage renal disease (ESRD) is manifested most commonly as acute uremic or dialysis pericarditis and infrequently as chronic constrictive pericarditis (CCP). We report a 27-year-old patient with a history of uncontrolled hypertension, end-stage-renal disease on hemodialysis, who presented with recurrent ascites, dyspnea, and hypotension. After diagnosis with CCP, a partial pericardiectomy was performed; however, the patient did not improve and a salvage total pericardiectomy soon followed. He continued to decompensate and expired following a terminal extubation. No definitive cause of constrictive pericarditis was found. Nonetheless, we surmise it may have developed secondary to his end-stage renal disease. A literature review revealed end-stage kidney disease as a relatively uncommon cause of CCP; only a few other such associations have thus far been reported.
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Kleynberg et al. (2011) conducted a case report in Chronic constrictive pericarditis and end-stage renal disease (n=1). End-stage renal disease was evaluated. A 27-year-old male with end-stage renal disease developed chronic constrictive pericarditis and expired despite partial and total pericardiectomy, highlighting a rare clinical association.
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