An Efficient Synthesis of 1‐Triacontanol Reduction of 12‐dodecanolide (1), readily accesible from cyclododecanone, with diisobutylaluminium hydride afforded a 98:2 mixture of 12‐hydroxydodecanal (3) and 2‐oxa‐1‐cyclotridecanol (2). Its reaction with triphenyloctadecylphosphorane yielded 12‐triaconten‐1‐ol (4), the catalytic hydrogenation of which gave a total yield of 68% of 1‐triacontanol (5) starting from cyclododecanone.
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Kirchner et al. (1985) studied this question.
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