Key result
A primary synovial sarcoma of the mediastinum in an 84-year-old woman exhibited an unusually slow volume doubling time of 568 days and progressive calcification over four years.
Case Report (n=1)
No
Highlights the importance of considering primary synovial sarcoma in the differential diagnosis of a primary intra-thoracic tumor, even with slow growth.
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Chest radiography showed a right posterior mass on the mediastinum of an 84-year-old woman. The mass had been growing gradually for four years. Surgical excision was performed, and a pathological examination found the mass to be consistent with primary synovial sarcoma (SS) of the mediastinum. To our knowledge, this is a rare case in which follow-up imaging was able to be performed over a period of four years. This disease is aggressive, and its early diagnosis is key to achieving a cure. It is important to consider primary SS in the differential diagnosis of a primary intra-thoracic tumor, even if the tumor grows slowly.
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Supports considering synovial sarcoma in mediastinal mass differentials; leaves open optimal management strategies.
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Kanemura et al. (2019) conducted a case report in Primary Synovial Sarcoma of the Mediastinum (n=1). Surgical resection was evaluated on Tumor volume doubling time (VDT). A primary synovial sarcoma of the mediastinum in an 84-year-old woman exhibited an unusually slow volume doubling time of 568 days and progressive calcification over four years.
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