Seven children with neuromuscular disease were placed on mechanical ventilation before the age of 2 years. The outcome for these patients was variable and did not correlate with primary diagnosis. There appeared to be a high correlation between the incidence of electrocardiogram changes and death. Our experience demonstrates that there was a high mortality rate (57%) in neuromuscular patients supported by mechanical ventilation before the age of 2 years.
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Iannaccone et al. (1988) studied this question.
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