Answers are grounded in this paper and cite their sources.
A library of C-alkyl and C-aryl nitrones has been obtained by direct condensation of primary N-substituted hydroxylamine hydrochlorides with various aldehydes and ketones without catalysts or base. The synthetic procedure, performed under MW irradiation in the absence of solvent, does not require the presence of a base, is fast, clean, high-yielding and characterized by simple work-up.
No takes yet. Share an insight, caveat, or question.
Maiuolo et al. (2015) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: