A novel monocyclic β-lactam antibiotic SQ 26, 180 has been isolated from bacteria and the structure, (R)-3-acetylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid was deduced from its spectroscopic properties. Structural confirmation and assignment of absolute configuration were made by synthesis from 6-aminopenicillanic acid.
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Parker et al. (1982) studied this question.
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