Defective Neutrophil Chemotaxis and Hyperimmunoglobulinemia E—a Reversible Defect?

An eleven‐month‐old boy is presented with chronic atopic dermatitis and recurrent infections of the skin and respiratory tract, including subcutaneous abscesses. Immunological studies disclosed a neutrophil chemotactic defect, blood eosinophilia and serum hyper IgE. The clinical and analytical data are similar to those of patients previously described by Hill & Quie. A diet free of the allergens which were responsible for the atopic dermatitis reversed the chemotactic defect, the blood eosinophilia and the clinical symptoms.