Synthese von [1,2,4]Triazolo [1,5‐a]chinazolinen. Ableitung der Konformation von Substituenten mit Hilfe der 13C‐NMR.‐Spektroskopie

Synthesis of [1,2,4]Triazolo[1,5‐a]quinazolines. Assignment of the Conformation of Substituents with the Aid of 13C‐NMR. Spectroscopy The synthesis of [1,2,4]triazolo[1,5‐a]quinazolines by condensation of 2‐hydrazinobenzoic acid with N‐cyano‐imidates is reported. The preferred conformation of substituents at C (5), e.g. N (CH3)2, N (CH3)NH2, N (CH3)OH, relative to the aromatic system is deduced with the aid of 13C‐NMR. chemical shifts and proton nuclear Overhauser effect experiments.