Apparent pK‐values have been determined for benzoic acid, trans‐cinnamic acid, picric acid, o‐chloro‐benzoic acid, p‐nitro‐phenol, quinine, brucine, sym‐diphenyl‐guanidine, 1, 2, 3‐triphenyl‐guanidine and (−)‐ephedrine in the solvent systems methylcellosolve/water and dimethylformamide/water as a function of the relative composition of these systems. The reproducibility of these values for a given range of the most important variables has been determined.
No takes yet. Share an insight, caveat, or question.
Simon et al. (1955) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: