A semi‐synthetic method for the preparation of deuterated leukotriene B4 (2H8‐LTB4) from eicosatetraynoic acid (ETYA) is described which involves reduction of ETYA to deuterated arachidonic acid (2H8‐AA) with deuterium gas and then biological conversion of this material to 2H8‐LTB4 by rat peritoneal polymorphonuclear leukocytes (PMNs).
No takes yet. Share an insight, caveat, or question.
Dawson et al. (1987) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: