Ultrasonically guided tissue core biopsy of the spleen was undertaken in eight patients with previously untreated non-Hodgkin's lymphoma in the staging procedure. In all cases, the tissue core specimens that were biopsied were sufficient to diagnose the presence of involvement of non-Hodgkin's lymphoma, and two of the eight were found to have histologic involvement. There was no complication in this series. It was concluded that this is a safe and reliable technique for the staging of malignant lymphoma.
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Suzuki et al. (1987) studied this question.
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