Concerning the Gastric Lesions Observed in Experimental Bacteremia

The frequency with which hemorrhage and erosions of the stomach mucosa are found in infections and intoxications has led some investigators to suggest the possibility of such conditions having a certain influence in the production of gastric ulcer. Although these lesions do at times simulate the so-called peptic ulcer, still there is considerable doubt as to whether they ever lead to the round or chronic gastric ulcer as it is observed in the human. It is almost impossible to say that any one factor acts as an exciting or contributing cause in the development of a gastric ulcer. The many theories which have been advanced illustrate the diversity of opinion, and we are today probaby little more advanced in solving the problem than were the early writers. The ideas concerning the effect of an altered blood stream on the gastric mucosa, bringing about ulceration, as well as the part played