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November 1, 1996Pacing and Clinical Electrophysiology

If Dr. Bazett Had Had a Computer…

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Key result

Computerized optimization of four generic QT/RR formulae provided a close fit to measured values, whereas the Bazett model overestimated QT intervals for slow heart rates.

Population

109 pairs of RR and QT intervals published by Dr. Bazett in 1920

Comparison

Computerized optimization of the QT/RR… vs The original Bazett model (QT = beta RR1/2)

Design

Other

Authors

MMMarek MalíkElectrophysiology

Discussion

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Overview

Clinicians should avoid Bazett correction at slow rates; leaves open optimal QT modeling pending prospective validation.

Structured PICO

P
Population
109 pairs of RR and QT intervals from Dr. Bazett's original 1920 data used to model the QT/RR relationship.
E
Exposure
Computerized optimization of the QT/RR relationship using four generic mathematical formulae
C
Comparator
The original Bazett model (QT = beta RR1/2)
O
Outcome
Minimum differences between actual QT intervals and values predicted by the model (goodness of fit)surrogate

Computerized optimization of historical QT/RR data demonstrates that the traditional Bazett formula overestimates QT intervals at slow heart rates, highlighting the importance of understanding model limitations.

Cite This Study

Marek Malík (1996) studied this question. Computerized optimization of QT/RR relationship vs. Bazett model was evaluated on Model fit (difference between actual and predicted QT intervals). Computerized optimization of four generic QT/RR formulae provided a close fit to measured values, whereas the Bazett model overestimated QT intervals for slow heart rates.

synapsesocial.com/papers/6a9ebf7c2aeffbb0cc11f21ehttps://doi.org/10.1111/j.1540-8159.1996.tb03191.x
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1The QT interval during reflex cardiovascular adaptation.1984 · 89 citations