Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands

Methods Study PopulationWe sought participation of all patients whose cases were reported to PHS between June 21 and July 2, 1999, and their household contacts, as well as all pupils from grade 1 (n = 48, 5 and 6 years of age) of the orthodox reformed elementary school.We requested two house calls, the first right before summer holidays (July 2), and the second right after the holidays (August 23).On the first visit, a questionnaire was completed and blood, saliva, oropharyngeal swab, and urine specimens were collected from all consenting household members, even those without symptoms.On the second visit, a questionnaire was completed, and blood and saliva specimens were obtained.On the first questionnaire, demographic variables, symptoms, and history of measles, measles vaccination status, travel abroad, and contact with measles were detailed.On the second visit, the section on symptoms was completed, if applicable, and two forms with additional questions were filled out.The first form inquired about complications, GP consultations, hospitalization, and medication.On the second form, limited information was gathered on all other household members (date of birth, sex, and recent measles infection).Pupils from grades 2 to 8 were sent the same questionnaires and additional questions before and after summer vacation.We received the names of pupils in grade 0 Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands