INTRODUCTION Not only is the pathogenicity of certain forms of tuberculosis of the skin still the subject of lively debate, but even the clinical and histopathologic features of certain presumably tuberculous diseases have not as yet been definitely cataloged nosologically. Certain well-known diseases, of which lupus vulgaris and tuberculosis verrucosa cutis are prototypes, have, of course, been long recognized as being due to the invasion of the skin by the bacillus of Koch. As time went on, and investigations progressed, other skin diseases were soon proved to be of tuberculobacillary nature; among these are lichen scrofulosorum, acute disseminated miliary tuberculosis, scrofuloderma, tuberculosis ulcerosa and lupus miliaris disseminatus faciei. These diseases may be designated as genuine tuberculoses of the skin. Investigations carried on in recent years have resulted in the inclusion, in this group, of two closely related affections, namely, the erythema induratum of Bazin and the subcutaneous sarcoid of Darier.
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Fred Wise (1921) studied this question.