Key result
Total aortic arch replacement surgery performed at a core temperature of 34 °C resulted in no neurological complications, aortic valve regurgitation, or anastomotic leaks in four patients.
Why the study?
Traditional aortic arch replacement surgery requires moderate or deep hypothermia and circulatory arrest, which can cause nervous system damage and frequent postoperative neurological complications.
Case Report (n=4)
No
Total aortic arch replacement at a core temperature of 34 °C using a middle arch clamping technique appears feasible and safe, potentially reducing circulatory arrest time and avoiding hypothermia-related neurological complications.
Supports 34 °C arch replacement feasibility in small series; hypothesis-generating and requires prospective validation before practice change.
BACKGROUND: Traditional aortic arch replacement surgery must be performed under moderate or deep hypothermia (22-28 °C) and circulatory arrest. Hypothermia and hypoperfusion can cause damage to the nervous system; therefore, postoperative brain and spinal cord complications are common. Improvements in surgical techniques are necessary to solve this problem. Herein, we report a method of total aortic arch replacement that can be performed at a core temperature of 34 °C, similar to other simple cardiac operations. CASE PRESENTATION: Four patients underwent surgery with this technique (3 males and 1 female, aged 48 to 67 years). Computed tomography angiography performed at admission showed a total aortic dissection, resulting in a diagnosis of Stanford type A aortic dissection. The patients underwent emergency aortic sinus remodelling, ascending aortic replacement, modified aortic arch replacement, and elephant trunk stenting. No patients had neurological complications. During a follow-up of more than 1-month, no patients had aortic valve regurgitation or anastomotic leak. CONCLUSIONS: This technique can increase the operating temperature by approximately 6 to 12 °C and reduce the circulatory arrest time by approximately 18 to 28 min. All of the patients recovered well without any neurological complications, demonstrating the feasibility and safety of this technique. We believe that this technique can serve as a good alternative strategy for managing aortic dissection and aneurysm, especially for young surgeons who are acquiring experience in arch replacement surgery.
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Li et al. (2019) conducted a case report in Stanford type A aortic dissection (n=4). Total aortic arch replacement surgery at 34 °C core temperature was evaluated on Neurological complications. Total aortic arch replacement surgery performed at a core temperature of 34 °C resulted in no neurological complications, aortic valve regurgitation, or anastomotic leaks in four patients.
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