Key result
Cervical epidural anaesthesia provided stable haemodynamics and excellent postoperative pain relief for a patient with severe doxorubicin-induced dilated cardiomyopathy undergoing modified radical mastectomy.
Case Report (n=1)
No
Cervical epidural anaesthesia may be a viable and hemodynamically stable option for patients with severe doxorubicin-induced cardiomyopathy undergoing modified radical mastectomy.
May support cervical epidural in select doxorubicin cardiomyopathy cases; hypothesis-generating and requires prospective validation.
Doxorubicin (Dox) is an antineoplastic agent used in a wide variety of malignancies. Its use is limited because of a cumulative, dose-dependent irreversible cardiomyopathy. We report a case of Dox induced cardiomyopathy, posted for modified radical mastectomy. The patient had poor LV function along with moderate pulmonary hypertension. Regional anaesthesia was planned as the risk associated with general anaesthesia was more. A cervical epidural was placed and a block adequate for surgery could be achived. The haemodynamic parameters as measured by esophageal doppler showed a stable trend. The surgery could be managed well under cervical epidural and also provided a good postoperative pain relief.
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Jain et al. (2013) conducted a case report in Doxorubicin-induced dilated cardiomyopathy (n=1). Cervical epidural anaesthesia was evaluated on Haemodynamic stability and pain relief. Cervical epidural anaesthesia provided stable haemodynamics and excellent postoperative pain relief for a patient with severe doxorubicin-induced dilated cardiomyopathy undergoing modified radical mastectomy.
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