Key result
Mini-access for aortic valve replacement was associated with similar 9-year survival compared to median sternotomy (85.9% vs 81.5%; P=0.34).
Why the study?
The study was conducted to compare the immediate and long-term results of sternotomy versus a mini-approach for aortic valve replacement.
Does mini-access compared to median sternotomy improve immediate and long-term outcomes in patients undergoing isolated aortic valve replacement?
Cohort (n=718)
Does mini-access compared to median sternotomy improve immediate and long-term outcomes in patients undergoing isolated aortic valve replacement?
Mini-access for aortic valve replacement provides similar immediate and long-term outcomes compared to median sternotomy.
Answers are grounded in this paper and cite their sources.
Mini-access may be considered in selected AVR patients; leaves open confirmation of equivalence by randomized trials.
Objective. To compare the immediate and long-term results of sternotomy and mini-approach for aortic valve replacement. Material and methods. A retrospective study included 718 patients who underwent isolated aortic valve replacement between April 2009 and December 2019. Propensity score matching was performed due to significant differences in clinical and demographic parameters. Two groups were distinguished: group I (sternotomy) — 67 patients, group II (mini-access) — 67 patients. Inclusion criteria: isolated aortic valve replacement, age ≥18 years. Exclusion criteria: Ross procedure, AVNeo, combined interventions, left ventricular ejection fraction≤40%, repeated interventions. The median follow-up period was 44 (7—80) months. Results. Duration of surgery, cardiopulmonary bypass and myocardial ischemia was similar in both groups (155 versus 165 min, p=0.4; 87 versus 92 min, p=0.4; 68 versus 70 min, p=0.4). There was no in-hospital mortality, stroke or perioperative myocardial injury. No significant difference was found in postoperative complications and length of ICU- and hospital-stay. Incidence of explorations for bleeding (3% vs 1.5%, p=0.9), pacemaker implantation (3% vs 1.5%, p=0.9), acute kidney injury (1.5% vs 0%, p=0.9) and sternal infection (0% vs 1.5%, p=0.9) was similar. One, 3-, 5- and 9-year survival was 100%, 100%, 94.7% and 81.5% after sternotomy, 100%, 91.1%, 85.9% and 85.9% after mini-access (p=0.34). Nine-year freedom from redo surgeries was 92% and 97%, respectively (p=0.84). Conclusion. There was no significant difference in immediate and long-term results.
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Enginoev et al. (2024) conducted a cohort in isolated aortic valve replacement (n=718). mini-access vs. median sternotomy was evaluated on 9-year survival (p=0.34). Mini-access for aortic valve replacement was associated with similar 9-year survival compared to median sternotomy (85.9% vs 81.5%; P=0.34).
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