Accommodation of a Single Protein Guest in Nanometer‐Scale Wells Embedded in a “DNA Nanotape”

All's well: A tapelike DNA scaffold with regularly arranged nanometer-scale wells is prepared by bundling nine DNA helices into U-shaped motifs (see picture). By attaching two biotin residues at two edges of each well, just one streptavidin tetramer is size-selectively captured to form a regularly oriented streptavidin nanoarray. The “anchored” tetramers nested in the wells are stable under repetitive AFM scanning.