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March 11, 2011Addiction

The pharmacodynamic and pharmacokinetic profile of intranasal crushed buprenorphine and buprenorphine/naloxone tablets in opioid abusers

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Authors

LMLisa S. MiddletonPNPaul A. NuzzoUniversity of KentuckyMLMichelle R. LofwallUniversity of Kentucky

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Middleton et al. (2011) studied this question.

synapsesocial.com/papers/6a9ec9baa2ef4b71f9478b0fhttps://doi.org/10.1111/j.1360-0443.2011.03424.x
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical pharmacology of buprenorphine: Ceiling effects at high doses1994 · 778 citations
  2. 2Effects of sublingually given naloxone in opioid-dependent human volunteers1990 · 71 citations