Mathematical modeling study demonstrates predictive accuracy for homeostatic changes in red blood cells, highlighting the utility of quantitative simulations in cell physiology.
Alexey Vereninov and collaborators pioneered the application of mathematical models of cellular homeostasis with ground-breaking contributions to the understanding of the mechanisms behind the dynamics of homeostatic changes in a variety of different cell types. As part of an issue dedicated to Vereninov’s memory, I thought that an example of the predictive potential of such models would be a fitting tribute to his work and achievements. The “Gardos effect” is the example chosen from our modelling experience.
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A 2022 study studied this question.
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