Key result
A combination of choline, inositol, methionine and vitamin B complex was more effective in reducing serum chylo and lipomicron counts than choline or inositol alone in coronary atherosclerosis.
Why the study?
Do lipotropic substances reduce serum chylomicron and lipomicron counts in patients with coronary atherosclerosis?
Do lipotropic substances reduce serum chylomicron and lipomicron counts in patients with coronary atherosclerosis?
In patients with coronary atherosclerosis, a combination of lipotropic agents (choline, inositol, methionine, vitamin B complex) synergistically reduces serum chylomicron and lipomicron counts.
Supports further study of lipotropic combinations; should not yet alter clinical management of atherosclerosis.
A technique for determining the response of serum chylomicron and lipomicron counts to the ingestion of lipotropic substances such as choline and inositol is described. 2. In a controlled series of patients with proven coronary atherosclerosis it was found that the lipotropic agent choline reduced serum chylo and lipomicron counts. Inositol did not display this activity when employed alone. 3. A synergistically acting combination of choline, inositol, methionine and vitamin B complex was more effective in reducing chylo and lipomicron counts than choline or inositol alone.
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Lester M. Morrison (1953) studied Coronary atherosclerosis. Combination of choline, inositol, methionine and vitamin B complex vs. Choline or inositol alone was evaluated on Serum chylomicron and lipomicron counts. A combination of choline, inositol, methionine and vitamin B complex was more effective in reducing serum chylo and lipomicron counts than choline or inositol alone in coronary atherosclerosis.
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