Genotype x diet interaction for litter size in mice

Substantial interaction was observed in 3 inbred strains of mice maintained on 5 normal commercial pelleted diets. Strain B10.BR was most sensitive to the unknown dietary factor, and the ranking of B10.BR and A2G was reversed across the array of diets. There was no apparent relationship between the ‘biological’ value of the diet and 21 dietary ingredients determined chemically. The study shows that the diet which gives the best performance for one strain of mice may not be the best for another.