Key result
In T2DM patients with subclinical hypothyroidism, dyslipidemia was associated with a 2.786 times higher prevalence of retinopathy compared to patients without dyslipidemia.
Why the study?
T2DM with subclinical hypothyroidism leads to higher retinopathy incidence, and subclinical hypothyroidism is linked to dyslipidemia, but the relationship between dyslipidemia and retinopathy in these patients is unknown.
Does dyslipidemia increase the risk of retinopathy in T2DM patients with subclinical hypothyroidism?
Cross-Sectional (n=278)
No
Does dyslipidemia increase the risk of retinopathy in T2DM patients with subclinical hypothyroidism?
Dyslipidemia is significantly associated with a higher prevalence of retinopathy in patients with type 2 diabetes and subclinical hypothyroidism.
Answers are grounded in this paper and cite their sources.
May guide retinopathy risk assessment in T2DM with subclinical hypothyroidism; leaves open causal effects and intervention benefits.
Background: Studies have shown type 2 diabetes mellitus (T2DM) accompanied by subclinical hypothyroid (SCH) leads to a higher retinopathy incidence, compared to T2DM without SCH. Furthermore, SCH patients are known to have a high risk of dyslipidemia. This study therefore aims to determine the relationship between dyslipidemia and retinopathy, in T2DM patients with SCH.Materials and Methods: This study used a cross-sectional design, and the study population consisted of adult patients diagnosed with T2DM over a year ago and visiting the Metabolic Endocrine Division’s outpatient ward at Cipto Mangunkusumo Hospital. The data collected include glycemic control, FT4, lipid profile TSHs, as well as retinopathy data.Results: According to the results, patients with T2DM and SCH accompanied by dyslipidemia, had a 2.76 times higher retinopathy risk, compared to patients without dyslipidemia (p value = 0.014). Conclusion: A significant relationship was concluded to exist between dyslipidemia and retinopathy in T2DM patients with SCH.International Journal of Human and Health Sciences Vol. 05 No. 04 October’21 Page: 478-483
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Hendarto et al. (2021) conducted a cross-sectional in Type 2 Diabetes Mellitus with Subclinical Hypothyroidism (n=278). Dyslipidemia vs. Without dyslipidemia was evaluated on Incidence of retinopathy (PR 2.786, 95% CI 0.890-8.718, p=0.014). In T2DM patients with subclinical hypothyroidism, dyslipidemia was associated with a 2.786 times higher prevalence of retinopathy compared to patients without dyslipidemia.
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