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January 1, 2020RSC AdvancesOpen Access

Synthesis and properties of DNA oligomers containing stereopure phosphorothioate linkages and C-5 modified deoxyuridine derivatives

Hiroya Kuwahara Reijiro Yoshino Yohei Nukaga Yusuke Maeda Kazuki Sato Takeshi Wada

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Abstract

p)-PS linkages in a DNA strand could significantly increase the thermal stability of a DNA/RNA hybrid duplex without reducing its RNase H activity.

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Kuwahara et al. (2020) studied this question.

synapsesocial.com/papers/6a9edbc3eabfa6230011f24a https://doi.org/10.1039/d0ra06970a

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