Key result
Chronic amiodarone after electrical cardioversion is associated with ~27% AF recurrence at two weeks.
Why the study?
Early recurrence of AF after electrical cardioversion is attributed to electrical remodeling, but the potential role of abnormal autonomic modulation had not been adequately tested.
Observational (n=93)
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Observational study demonstrates autonomic influence on early atrial fibrillation recurrence in cardioverted patients, highlighting heart rate variability as an indicator of arrhythmic risk.
Lombardi et al. (2001) conducted an observational in Persistent atrial fibrillation (n=93). Heart rate variability (HRV) was evaluated on Atrial fibrillation recurrence at 2 weeks. Among 93 patients with persistent atrial fibrillation on chronic amiodarone treatment after electrical cardioversion, 25 experienced AF recurrence at 2 weeks.
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