From Race-Based to Equity-Informed Antihypertensive Medication Selection: Rationale for the 2025 AHA/ACC Guideline Change

“This broader, more personalized approach gives clinicians a better idea of which people with hypertension would benefit most from treatment.”

“The PREVENT score calculator does not include race as a determinant, addressing longstanding concerns about the equity and appropriateness of race-based metrics in clinical care.”

“The PREVENT equations deliberately removed race from the equation as a trade-off between equity, generalizability, and precision in risk prediction. The developers of PREVENT emphasized race as a social construct and not a biological determinant, resulting in race-free, sex-specific models to avoid biases in clinical decision-making.”