A Cu‐catalyzed remote sp3 CH/unactivated alkenes functionalization reaction for the concomitant construction of CCF3 and CO bonds was described. An 1,5‐H radical transfer involving an sp3 CH bond adjacent to a nitrogen atom and an α‐CF3‐alkyl radical intermediate derived from unactivated alkenes was observed and demonstrated to proceed via the radical process.
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Li et al. (2016) studied this question.
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