A completely linear transform of the multi-target survival curve is presented. This enables all data, including those on the shoulder region of the curve, to be analysed. The necessity to make a subjective assessment about which data points to exclude for conventional methods of analysis is, therefore, removed. The analysis has also been adapted to include a "Pike-Alper" method of assessing dose modification factors. For the data cited this predicts compatibility with the hypothesis of a true oxygen "dose-modification" whereas the conventional Pike-Alper analysis does not.
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James Watson (1978) studied this question.
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