Study of Some Analogue of Currently Clinically Used Antimycobacterial Agents

The considerable interest in the research and development of new molecules with anti mycobacterial activity par- ticularly against multidrug resistance (MDR) and extensively drug resistant (XDR) tuberculosis (TB) because mycobacterium species have developed resistant against currently used drugs. The currently use anti-TB agents having toxic effect and long period of therapy. Therefore, many researchers have synthesized various analogues of currently used antiTB agents for anti-TB activity. These explanation have been directing for the development of new molecules that hold potent anti-TB activity with minimum adverse or side effects and also effective against MDR-TB, XDR-TB mycobacterium, and also in patient coinfected with HIV/AIDS.