A carbonized porous silicon Fabry–Perot film acts as an electrically addressable, label-free optical biosensor that allows simultaneous separation, capture, and detection of charged proteins within a volume of 5 nL. Electroadsorption of protein within the 40 nm diameter pores is induced by an applied bias and the process is monitored in real-time by optical interferometry.
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Chen et al. (2011) studied this question.
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