Key result
Additional low-speed rotational atherectomy following high-speed rotational atherectomy ablated more plaque volume and gained a larger minimum lumen area compared with high-speed rotational atherectomy alone.
Why the study?
Does additional low-speed rotational atherectomy following high-speed rotational atherectomy improve plaque ablation and lumen area in patients with heavily calcified coronary lesions?
Does additional low-speed rotational atherectomy following high-speed rotational atherectomy improve plaque ablation and lumen area in patients with heavily calcified coronary lesions?
Additional low-speed rotational atherectomy following high-speed rotational atherectomy may improve plaque ablation and lumen area in heavily calcified lesions without increasing burr lodging.
Clinical outcomes of percutaneous coronary intervention (PCI) have been improving due to evolutions such as development of new-generation drug-eluting stents, use of intracoronary imaging device and widespread use of optimal medical therapy 1 .Nevertheless, current PCI has not achieved outcomes comparable to coronary artery bypass grafting (CABG) 2-3 , especially in patients with complex lesions such as heavily calcified lesions.Rotational atherectomy (RA) is one of the important options for heavily calcified lesions in PCI.However, the clinical adverse event rate in PCI requiring RA has been high in real-world practice 4 .To improve clinical outcomes of PCI requiring RA, some important procedural points should be addressed.First, avoiding life-threatening complications such as coronary perforation should be the bottom-line requirement for the appropriate practice.Second, procedural management for preventing large periprocedural myocardial injury would be essential.Previous reports have suggested that large periprocedural myocardial infarctions were associated with a substantial increase in subsequent mortality 5 .Third, adequate ablation for optimal stent expansion is important.
No takes yet. Share an insight, caveat, or question.
Yamamoto et al. (2020) conducted an editorial in Heavily calcified coronary lesions. Additional low-speed rotational atherectomy (LS-RA) following high-speed rotational atherectomy (HS-RA) vs. High-speed rotational atherectomy (HS-RA) only was evaluated on Plaque volume ablation and minimum lumen area. Additional low-speed rotational atherectomy following high-speed rotational atherectomy ablated more plaque volume and gained a larger minimum lumen area compared with high-speed rotational atherectomy alone.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: