Key result
Sleeve gastrectomy is associated with a risk of exacerbating pre-existing gastroesophageal reflux disease or developing de novo disease.
Why the study?
Despite sleeve gastrectomy being widely performed, recent data reveal a risk of exacerbation of pre-existing GERD or development of de novo GERD following the procedure.
Sleeve gastrectomy carries a risk of exacerbating or causing de novo GERD, necessitating specific management and treatment paradigms.
Alerts clinicians to GERD risk after sleeve gastrectomy; leaves open optimal prevention and management strategies for prospective trials.
Obesity is associated with serious comorbidities and economic implications. Bariatric surgery, most commonly Roux-en-Y gastric bypass and sleeve gastrectomy, are effective options for weight loss and improvement of obesity-related comorbidities. With the growing obesity epidemic, there has been a concomitant rise in bariatric surgeries, particularly in sleeve gastrectomy, which has been the most widely performed bariatric surgery since 2013. Gastroesophageal reflux disease (GERD) is highly prevalent in obese individuals, can significantly impact quality of life and may lead to serious complications. Obesity and GERD both improve with weight loss. However, as the incidence of sleeve gastrectomy rises, recent data has revealed a risk of exacerbation of pre-existing GERD or the development of de novo GERD following sleeve gastrectomy. We performed a detailed review of GERD post-sleeve gastrectomy, including its overall incidence, pathophysiology and current treatment paradigms.
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Masood et al. (2024) conducted a review in Gastroesophageal reflux disease (GERD) following sleeve gastrectomy. Sleeve gastrectomy was evaluated. Sleeve gastrectomy is associated with a risk of exacerbating pre-existing gastroesophageal reflux disease or developing de novo disease.
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