This article firstly summarizes various technologies of structural molecular biology, and the study objects, equipment types, advantages/disadvantages of each equipment have become the emphasis of the review part in this essay. Then the limitations of DNA sequencing technology have been critically discussed. Instead, the molecular structural biology technology becomes the alternative to further characterize the genetic information in more exact way, which focus on the spatial distribution of DNA sequences inside DNA structure. A novel method of DNA structure observation is designed, which is convenient and cheaper for practical application, and a bottom-up method is advised to screen both function and structure for specific enzyme species.
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Huan Liu (2022) studied this question.
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