1,5-Dienes containing an allylsilane are cyclized by Lewis acids to methylenecyclohexanes. The trimethylsilyl group exerts a strong activating and directing influence on the regioselectivity of this cyclization. The monocyclic compound 10 was converted into the diterpene, (±)-trixagol (3).[Formula: see text]
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Armstrong et al. (1983) studied this question.
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