Key result
Preoperative statin therapy did not significantly reduce the incidence of postoperative atrial fibrillation compared to no statin use in patients undergoing isolated coronary artery bypass grafting (28.1% vs 29.7%, p=0.764).
Why the study?
Do preoperative statins prevent the development of post operative atrial fibrillation in patients undergoing coronary bypass surgery?
Cohort (n=854)
No
Do preoperative statins prevent the development of post operative atrial fibrillation in patients undergoing coronary bypass surgery?
Preoperative statin use does not appear to protect against postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting.
Answers are grounded in this paper and cite their sources.
Suggests preoperative statins should not be prescribed solely for postoperative AF prophylaxis in CABG; leaves open.
In a propensity-matched cohort of patients undergoing coronary bypass surgery, we could not demonstrate that preoperative statins were protective for the development of post operative atrial fibrillation.
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Paturi et al. (2011) conducted a cohort in Coronary artery bypass grafting (CABG) (n=854). Preoperative statin therapy vs. No preoperative statin therapy was evaluated on Incidence of postoperative atrial fibrillation (p=0.764). Preoperative statin therapy did not significantly reduce the incidence of postoperative atrial fibrillation compared to no statin use in patients undergoing isolated coronary artery bypass grafting (28.1% vs 29.7%, p=0.764).
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