Key result
Cilostazol demonstrates consistent efficacy in improving exercise capacity and overall health-related quality of life in patients with intermittent claudication.
Why the study?
Does cilostazol improve exercise capacity and quality of life in patients with intermittent claudication?
Does cilostazol improve exercise capacity and quality of life in patients with intermittent claudication?
This review highlights the efficacy of cilostazol in improving exercise capacity and quality of life for patients with intermittent claudication.
Answers are grounded in this paper and cite their sources.
May support symptom management in intermittent claudication; leaves open the need for updated RCTs to inform guidelines.
Safety and efficacy of cilostazol in the management of intermittent claudication Yung-Wei Chi, Carl J Lavie, Richard V Milani, Christopher J WhiteDepartment of Cardiology, Ochsner Clinic Foundation, New Orleans, LA, USAAbstract: Peripheral arterial disease (PAD) is a major health problem affecting millions of patients worldwide. Many will suffer from intermittent claudication (IC), which leads to marked impairment of quality of life (QoL). Besides surgical and endovascular interventions to improve limb-specific outcomes, pharmacotherapy is an effective tool in the treatment of IC. Cilostazol, a Federal Drug Administration-approved medication for the treatment of IC, has demonstrated consistent efficacy in improving exercise capacity and overall health-related QoL. This manuscript will review the pharmacokinetics, safety, and efficacy of cilostazol in the treatment of patients with IC as well as compare this agent with other proven non-invasive therapies for PAD.
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Yung‐Wei Chi (2008) conducted a review in Intermittent claudication. Cilostazol vs. Other proven non-invasive therapies was evaluated. Cilostazol demonstrates consistent efficacy in improving exercise capacity and overall health-related quality of life in patients with intermittent claudication.
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