S tudies indicate that diabetes affectsmood, cognitive function, and mo-tor performance (1–5). As cognitive dysfunction and depressive mood symp-toms have been reported with hypergly-cemia (5–7), we hypothesized that the impact of insulin on blood glucose pa-rameters would affect mood and cognitive symptoms. Consistent with our past post hoc findings (7), we specifically hypothe-sized that rapid pre- to postmeal blood glucose rate of change (BGRATE) corre-lates with negative mood and cognitive postmeal symptoms but not with energy or positive mood. We report the results of correlation analyses of BGRATE with symptoms from a pilot investigation de-
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Cox et al. (2007) studied this question.
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