OBJECTIVE: The author reports symptomatic spinal canal stenosis due to degenerative spondylolisthesis at L4-5 in identical twins. SUMMARY OF BACKGROUND DATA: The patient reported his brother had a similar condition. METHODS: Monozygosity was established by phenotyping. CONCLUSIONS: Spinal morphology and degenerative disease may be genetically determined.
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Michael D. Ryan (1994) studied this question.